David Goode
Team Leader: Computational Cancer Biology
Medicine
Peter MacCallum Cancer Centre
Australia
Biography
Dr. Goode is a Team Leader in the Computational Cancer Biology Program, where he heads the Evolutionary Cancer Genomics group. His research applies bioinformatics, molecular evolution and population genetics to large cancer genomics data sets to study the evolutionary forces governing the formation of tumours and their responses to therapy. All projects in my group are highly collaborative, teaming with a number of leading groups in prostate cancer, breast cancer and sarcoma research at the Peter Mac and beyond.
Research Interest
Bioinformatics, Cancer Genomics, Tumour Evolution, Population Genetics
Publications
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Ballinger ML, Goode DL, Ray-Coquard I, James PA, Mitchell G, Niedermayr E, Puri A, Schiffman JD, Dite GS, Cipponi A, Maki RG, Brohl AS, Myklebost O, Stratford EW, Lorenz S, Ahn SM, Ahn JH, Kim JE, Shanley S, Beshay V, Randal RL, Judson I, Seddon B, Campbell IG, Young MA, Sarin R, Blay JY, O’Donoghue SI, and Thomas DM for the International Sarcoma Kindred Study. Monogenic and polygenic determinants of sarcoma risk: an international genetic study. The Lancet Oncology. 17(9):1261-71 (2016).
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Kader T, Goode DL (2016), Wong SQ, Connaughton J, Rowley SM, Devereux L, Byrne D, Fox SB, Mir Arnau G, Tothill RW, Campbell IG, Gorringe KL. Copy number analysis by low coverage whole genome sequencing using ultra low-input DNA from formalin-fixed paraffin embedded tumor tissue. Genome Medicine. 8(1):121.
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Trigos AS, Pearson RB, Papenfuss AT, Goode DL (2017). Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors. Proceedings of the National Academy of Sciences USA. 114(24):6406-6411.
