Ian Campbell
ProfessorÂ
Medicine
Peter MacCallum Cancer Centre
Australia
Biography
Professor Campbell is co-Head of the Cancer Genomics and Genetics Program at the Peter MacCallum Cancer Centre and Professor in the Sir Peter MacCallum Department of Oncology at the University of Melbourne, Australia. Professor Campbell’s laboratory is regarded as one of Australia’s leading breast and ovarian cancer genetics facilities. His laboratory has particular international recognition for work on the discovery of new familial breast and ovarian cancer predisposition genes through exome sequencing and large scale targeted sequencing approaches. Professor Campbell has also made a series of seminal contributions to the understanding of the etiology of ovarian cancer and continues a leading international role into somatic molecular analyses of breast and ovarian cancer precursor lesions. He is the lead investigator of Lifepool, which is a cohort of 54,000 women attending Breast Screening services. Lifepool (www.lifepool.org) provides an internationally unique resource capable of providing definitive answers to critical questions in breast cancer epidemiology and biology.
Research Interest
Cancer Genetics and Genomics
Publications
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Thompson ER, Boyle SE, Johnson J, Ryland GL, Sawyer S, Choong DY, kConFab, Chenevix-Trench G, Trainer AH, Lindeman GJ, Mitchell G, James PA, Campbell IG. Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients. Hum Mutat. 2012 Jan;33(1):95-9.
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Thompson ER, Doyle MA, Ryland GL, Rowley SM, Choong DY, Tothill RW, Thorne H; kConFab, Barnes DR, Li J, Ellul J, Philip GK, Antill YC, James PA, Trainer AH, Mitchell G, Campbell IG. Exome sequencing identifies rare deleterious mutations in DNA repair genes FANCC and BLM as potential breast cancer susceptibility alleles. PLoS Genet. 2012 Sep;8(9):e1002894.
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Thompson ER, Rowley SM, Li N, McInerny S, Devereux L, Wong-Brown MW, Trainer AH, Mitchell G, Scott RJ, James PA, Campbell IG. Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care. J Clin Oncol. 2016 May 1;34(13):1455-9.
