Sarah Ellis
Associate Professor
Medicine
Peter MacCallum Cancer Centre
Australia
Biography
Prof Ellis leads a team of experienced staff members who are dedicated in maintaining the microscopes and ancillary equipment to the highest standard and supporting the researchers using the facility. She is also a member of the Cancer Immunology Program, where through successful NHMRC grant funding, she is able to pursue her research interests investigating the role of polarity proteins in leukaemia and lymphoma. Polarity proteins are responsible for maintaining the apical-basal polarity of cells and are evolutionary conserved from Drosophila to humans. Research has revealed a role for these proteins in the development of many cancers but their role in blood cancers, leukaemia and lymphoma, is still in its infancy and presents an exciting opportunity for research.
Research Interest
OPTICAL MICROSCOPY, ELECTRON MICROSCOPY, HISTOLOGY, HAEMATOPOIETIC STEM CELLS, POLARITY PROTEINS
Publications
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Combined deficiency of PI3KC2 alpha and PI3KC2 beta reveals a nonredundant role for PI3KC2 alpha in regulating mouse platelet structure and thrombus stability 2016
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The Asymmetric Cell Division Regulators Par3, Scribble and Pins/Gpsm2 Are Not Essential for Erythroid Development or Enucleation. PLoS One. 12. 2017
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Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting. Clinical Cancer Research. 23. 2017
