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Ross Barnetson

Emeritus Professor
Dermatology
The University of Sydney
Australia

Biography

Ross Barnetson trained in Medicine at Edinburgh University between 1958 and 1964. For three years during his medical training he served in the Territorial Army in the Airborne Division of the British Army. He also performed electives in Israel and the USA. After graduating in Edinburgh he joined the regular Army, and after training in Tropical Medicine was stationed in Cyprus for 2 years, where he worked at the British Military Hospital, Dhekelia and was a member of the Near East Parachute Force providing medical cover for the force. He was then stationed in West Malaysia and Singapore working in two Military Hospitals in Tropical Medicine. He retired from the army after 5 years. On leaving the army in 1970 he returned to Edinburgh and was appointed as a Registrar in Dermatology in the Professorial Unit at the Royal Infirmary. He became a member of the Royal College of Physicians (MRCP) by examination and continued as a Registrar in Dermatology for 3 years writing papers on a number of skin diseases such as dermatitis herpetiformis (a form of coeliac disease) and fungal infections. In 1974, he was appointed as a MRC Clinical Research Physician in Addis Ababa, Ethiopia working in the Armauer Hansen Research Institute. He performed a study of reversal reactions in leprosy and wrote his MD thesis on this subject. He wrote 10 papers on leprosy, and leishmaniasis, including one in Nature, one in Lancet and one in the British Medical Journal. In 1976, he returned to Edinburgh University as a lecturer in Dermatology, and continued as such till 1981: this included a six month period in immunology working with Prof Ivan Roitt FRS. As a lecturer he completed 30 papers on skin diseases mainly on allergy and atopic dermatitis. He was then appointed as a consultant and senior lecturer at the Royal Infirmary Edinburgh and Edinburgh University, where he continued until being appointed to the Chair of Dermatology at the University of Sydney in 1988. He was elected to be a Fellow of the Royal College of Physicians (London) and a Fellow of the Royal College of Physicians of Edinburgh. Between 1978 and 1987 he was a WHO consultant in leprosy paying several visits to India, Iran and Indonesia. During this time he wrote 30 further scientific papers on skin diseases and 15 chapters in books, both dermatological and immunological. One of these chapters describes for the first time, the concept of ATOPIC (ALLERGIC) MARCH (Barnetson and Gawkrodger). On taking up the Chair of Dermatology at the University of Sydney in 1988 which was the first Chair of Dermatology in Australia, he established laboratory research in Dermatology in Australia. As well as building up the clinical Department of Dermatology at Royal Prince Alfred Hospital, two large laboratories were commandeered and created into modern immunological laboratories under the supervision of Professor Gary Halliday, immunologist and world authority on skin cancer, and its prevention. Curriculum Vitae: Ross Barnetson 2 Australia has the highest incidence of skin cancer in the world, and 400,000 new cases present each year, so it is a huge clinical problem in Australia, worthy of major research. Probably the most important observation was that reported in the Proceedings of the National Academy of Sciences in the USA which showed that UVA is as important as UVB in the development of skin cancer and thus sunscreens need to protect effectively against UVA as well as UVB. In 1988, Ross Barnetson founded and became the Director of the Dermatology Research Foundation with Sir John Carrick as President. In the time he was in the Chair of Dermatology this raised more than $1 million for research funding. In 2002, Mr John Conde AO succeeded Sir John Carrick as President of the Foundation. In 2003 Ross founded the Australasian Society for Dermatology Research, and was the Founding President for 2 years. He remains on the Board of this Society which continues to be well attended by scientists and dermatologists. During this time as Professor of Dermatology at the University of Sydney, he was also part of the Pacific Islands Project, run by the Royal Australasian College of Surgeons. He was responsible for the Dermatology arm of the project, which ran from 1996 – 2003. He himself paid visits to Samoa, Vanuatu, Fiji and Tuvalu, seeing patients with skin diseases, and teaching the local medical and nursing staff. He received a commendation for this from the Australian Government. During his 18 years as Professor of Dermatology he was co-author of 100 papers, and by the time he retired he had 30 full time research staff working with him, by far the largest Department of Dermatology in Australia. He handed over the Chair of Dermatology to Professor Wolfgang Weninger in 2007 who had trained in Vienna as a dermatologist and then worked at Harvard and the Wistar Institute in Philadelphia. The Department now has 40 full time research personnel and is well recognised around the world for the importance of its research. The department has published over 400 scientific papers and attracted more than $20 million in grants. In 2010, Ross Barnetson was awarded a silver medal by the Australasian College of Dermatologists, in recognition of his success in founding a Chair of Dermatology in Australia, and developing two large laboratory complexes for dermatology at the University of Sydney, the first Dermatology Research Laboratories in Australia.

Research Interest

 Dermatology

Publications

  • DNAzyme Targeting c-jun Suppresses Skin Cancer Growth.

  • Destroying c-Jun Messenger: New Insights into Biological Mechanisms of DNAzyme Function.

  • Safety and tolerability of an intratumorally injected DNAzyme, Dz13, in patients with nodular basal-cell carcinoma: a phase 1 first-in-human trial (DISCOVER).

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