Adam Ewing
Research Fellow
Department of Biomedical Sciences
Translational Research Institute
Australia
Biography
My current work involves the analysis of sequence data in its many forms, particularly methods for improving mutation detection and inferring the functional consequences of mutations. I have a strong interest in retrotransposition: the process by which pieces of genomes are duplicated and inserted at distal locations.
Research Interest
Genomics, Bioinformatics
Publications
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Ewing AD*#, Houlahan KE*, Hu Y*, Ellrott K, Caloian C, Yamaguchi TN, Bare JC, P'ng C, Waggott D, Sabelnykova VY, Kellen MR, Norman TC, Haussler D, Stolovitzky G, Margolin AA, Stuart JM, Friend SH, Boutros PC. Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection. 2015. Nature Methods. 12:623-30.
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Ewing AD, Gacita A, Wood LD, Ma F, Xing D, Kim MS, Manda SS, Abril G, Pereira G, Makohon-Moore A, Looijenga LH, Gillis AJ, Hruban RH, Anders RA, Romans KE, Pandey A, Iacobuzio-Donahue CA, Vogelstein B, Kinzler KW, Kazazian HH Jr, Solyom S. Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution. 2015. Genome Res. 25:1536-45.
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Ewing AD#. Transposable element detection from whole genome sequence data. 2015. Mobile DNA 6:24.
