Grant Buchanan

Biography

Dr Buchanan leads a dynamic and contemporary research team, the Cancer Biology Group, at the Basil Hetzel Institute for Translational Research. This research group aims to fuse innovative molecular technology to pertinent clinical questions. The overall research objectives are to (i) provide a more holistic insight into the determinants of cancer initiation and progression, (ii) define comprehensive network models of nuclear receptor function in normal cells and in cancer, (iii) identify the inter-relationship between nuclear receptor networks, paracrine signalling and the cellular and tumour microenvironment, and (iv) generate and disseminate tools and reagents for nuclear receptor research. During Dr Buchanan's PhD and early postdoctoral studies, he was mentored by Professors Villis Marshall and Wayne Tilley, who are internationally regarded for their work on androgen receptor (AR) in prostate cancer. Between 2006-2007, Dr Buchanan conducted the overseas component his CJ Martin Fellowship at the University of Southern California under the mentorship of Professors Gerry Coetzee, Mike Stallcup and Ron Ross (dec.). Working with that highly regarded and multidisciplinary team, Dr Buchanan established skills and resources in genome-scale analysis of steroid receptor action, cofactors, ChIP-chip, Chip-seq, transcription profiling, microarray, bioinformatics and network analysis, and established a set of strategic international collaborations. Returning to Australia, Dr Buchanan received one of only four nationally awarded Young Investigator Awards (2007) from the Prostate Cancer Foundation of Australia. In recognition of his research to date, in 2010 CIA Buchanan was awarded the Prostate Cancer Foundation of Australia National Young Researcher of the Year. Dr Buchanan has held several prestigious research training fellowships; first from the Cancer Council of South Australia, a training award from the United States Department of Defense, a NHMRC CJ Martin Fellowship and lastly a NHMRC CDA Level A. Over the last 10 years, CIA Buchanan has supervised 7 Honours students (6/7 attaining first class; 2 as principal) and 8 PhD students (5 awarded, 3 current; 5 as principal).

Research Interest

Medicine,Medical Education,Research,etc