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Bioinformatics & Systems Biology Experts

David James

Professor
Biology
University of Sydney
Australia

Biography

Dr.DAVID JAMES is a Professor of Biology at Charles Perkins Centre. David James was awarded a PhD in 1985 in Physiology and Biochemistry from UNSW. During this period, together with colleagues at the Garvan Institute, he developed novel methodologies for studying in vivo glucose metabolism in small animals leading to a number of important discoveries about the role of tissue specificity of insulin action at the whole body level.In 1985 he was awarded a Fogarty fellowship and later a Juvenile Diabetes Foundation fellowship to undertake postdoctoral training at Boston University with Paul Pilch and subsequently at Washington University in St Louis. During this period he provided cellular and molecular evidence to document the identity and behaviour of the insulin responsive glucose transporter GLUT4.

Research Interest

Biology

Publications

  • Nelson, M., Lahiri, S., Chow, J., Byrne, F., Hargett, S., Breen, D., Olzomer, E., Wu, L., Cooney, G., Turner, N., James, D., et al (2017). Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival. Nature Communications, 8, 1-11.

  • Krycer, J., Fisher-Wellman, K., Fazakerley, D., Muoio, D., James, D. (2017). Bicarbonate alters cellular responses in respiration assays. Biochemical and Biophysical Research Communications, 489, 399-403.

  • Norris, D., Yang, P., Krycer, J., Fazakerley, D., James, D., Burchfield, J. (2017). An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction. Journal of Cell Science, 130, 2757-2766.

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