Georges Grau
Professor
Pathology
University of Sydney
Australia
Biography
Dr. GEORGES GRAU is a Professor and Chair of Vascular Immunology, Department of Pathology at School of Medical Sciences and Faculty of Medicine at University of Sydney
Research Interest
Immunopathology of microvascular lesions, particularly of cerebral and pulmonary complications of infectious and auto-immune diseases, especially in cerebral malaria, septic shock and multiple sclerosis. Analysis of the cellular and molecular mechanisms of the interactions between microvascular endothelial cells and cells of the immune system. Experience in various in vivo and in vitro experimental systems as well as in clinical studies. More recently, focus on the neurovascular lesion of murine and human cerebral malaria, using co-culture model systems involving brain endothelium, P. falciparum infected erythrocytes, as well as circulating cells, particularly platelets and monocytes.
Publications
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Whittington, C., Danastas, K., Grau, G., Murphy, C., Thompson, M. (2017). Expression of VEGF111 and other VEGF-A variants in the rat uterus is correlated with stage of pregnancy. Journal of Comparative Physiology B, 187(2), 353-360.
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Maknitikul, S., Luplertlop, N., Grau, G., Ampawong, S. (2017). Dysregulation of pulmonary endothelial protein C receptor and thrombomodulin in severe falciparum malaria-associated ARDS relevant to hemozoin. PloS One, 12(7), 1-22.
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Marzook, N., Latham, S., Lynn, H., McKenzie, C., Chaponnier, C., Grau, G., Newsome, T. (2017). Divergent roles of beta- and gamma-actin isoforms during spread of vaccinia virus. Cytoskeleton, 74(4), 170-183.
