Ian Alexander
Professor
Paediatrics
University of Sydney
Australia
Biography
Dr.Ian Alexander is a Professor of Paediatrics & Molecular Medicine Disciplines of Child and Adolescent Health and Genetic Medicine at The Children's Hospital at Westmead
Research Interest
Prof Alexander's specific expertise and interests include virus-mediated gene transfer with a focus on target organs including the liver and bone marrow, both of which have immense promise as target organs for the treatment of genetic disease in children. His team became the first in Australia to treat a genetic disease (SCID-X1) by gene therapy and are recognised leaders in the establishment of this exciting field in Australia.
Publications
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Ginn, S., Hallwirth, C., Liao, S., Teber, E., Arthur, J., Wu, J., Lee, H., Tay, S., Hu, M., Reddel, R., Alexander, S., Alexander, I., et al (2017). Limiting Thymic Precursor Supply Increases the Risk of Lymphoid Malignancy in Murine X-Linked Severe Combined Immunodeficiency. Molecular Therapy - Nucleic Acids, 6, 1-14
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Baruteau, J., Waddington, S., Alexander, I., Gissen, P. (2017). Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects. Journal of Inherited Metabolic Disease (JIMD), 40(4), 497-517
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Baruteau, J., Waddington, S., Alexander, I., Gissen, P. (2017). Delivering efficient liver-directed AAV-mediated gene therapy. Gene Therapy, 24, 263-264
