Michael Davies
Professor
Medicine
University of Sydney
Australia
Biography
Michael Davies was awarded his B.Sc. and D.Phil. degrees from University of York, UK. He completed a post-doctoral position at Brunel University, before returning to the University of York as a staff member. In 1995 he moved to the Heart Research Institute, Sydney, Australia, where he worked as a Group Leader, Deputy Director and then Director, as well as holidng the title of Professor at the University of Sydney.
Research Interest
Prof. Davies' research interests lie in the mechanisms of protein modification by reactive species (radicals, two-electron oxidants, glycation reactions), the biological consequences of such reactions, and the development of methods to quantify protein damage in disease. He also has interests in EPR spectroscopy for the detection of transient radicals, the kinetics of oxidant reactions, extracellular matrix damage and the development of antioxidants.
Publications
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•Love, D., Barrett, T., White, M., Cordwell, S., Davies, M., Hawkins, C. (2016). Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages. Free Radical Biology and Medicine, 94, 88-98.
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•Kovacevic, Z., Sahni, S., Lok, H., Davies, M., Wink, D., Richardson, D. (2017). Regulation and control of nitric oxide (NO) in macrophages: Protecting the "professional killer cell" from its own cytotoxic arsenal via MRP1 and GSTP1. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics, 1861 (5), 995-999. [
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•Carroll, L., Pattison, D., Fu, S., Schiesser, C., Davies, M., Hawkins, C. (2017). Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes. Redox Biology, 12, 872-882.
