Nicholas Buckley
Professor
Pharmacology
University of Sydney
Australia
Biography
Dr.Nicholas Buckley is a Professor of Clinical Pharmacology Pharmacology at School of Medical Sciences
Research Interest
Mechanisms and outcomes from acute kidney injury after poisoning/snakebite • Effect of pesticide bans and safe storage of pesticides • Descriptive studies of the mechanism of toxicity of a range of pesticide poisonings • Comparisons of the relative toxicity of different pesticides • Measurement of long-term neurotoxicity after acute poisoning • Trials of regulatory restrictions and reformulation of pesticides • Evaluation of investigations used in poisoning • Clinical trials of existing antidotes for poisoning • Development of new antidotes for poisoning • Clinical trials comparing different strategies to manage snakebite • Systematic reviews of treatments of poisoning • Developmenttal toxicity from pesticides • Paracetamol poisoning • Pharmacometrics - modelling of drug concentrations and effects. • Cardiotoxicity of psychotropic drugs • Toxicovigilance - detection of emerging toxicological problems • Epidemiology of poisoning and drug abuse • Coronial data on lethal poisoning and adverse drug effects • Pharmaco-epidemiology studies on adverse drug effects and drug interactions
Publications
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Blanch, B., Gladstone, E., Smolina, K., Buckley, N., Karanges, E., Morgan, S., Pearson, S. (2017). Benchmarking prescription drug access patterns in pharmaceutical claims: a method for identifying high and potentially harmful opioid use in Australia and Canada? Journal of Pharmaceutical Health Services Research, 8(1), 23-30.
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Silva, A., Maduwage, K., Buckley, N., Lalloo, D., de Silva, H., Isbister, G. (2017). Antivenom for snake venom-induced neuromuscular paralysis [intervention protocol]. Cochrane Database of Systematic Reviews, 2017 (3), 1-10
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Isbister, G., Jayamanne, S., Mohamed, F., Dawson, A., Maduwage, K., Gawarammana, I., Lalloo, D., de Silva, H., Scorgie, F., Lincz, L., Buckley, N. (2017). A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming. Journal of Thrombosis and Haemostasis, 15(4), 645-654
