Patrick Bertolino
Professor
Immunology
University of Sydney
Australia
Biography
Patrick Bertolino leads the Liver Immunology Group and has been a Faculty member at the Centenary Institute since 2011. He is considered one of the leading experts in Liver Immunology internationally, and is acknowledged as the leader in this field in Australia, where he drives the main group working in this new and expanding discipline.
Research Interest
The liver immunology group is studying the unique relationship between the liver and the immune system. Livers dampen down immunity to such an extent that they can be transplanted without rejection in some cases. Livers may not only be tolerated, but may also prevent the rejection of other organ grafts from the same donor, a process known as immune tolerance.
Publications
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Lovelace, M., Powter, E., Coleman, P., Zhao, Y., Parker, A., Chang, G., Lay, A., Hunter, J., McGrath, A., Jormakka, M., Bertolino, P., McCaughan, G., Vadas, M., Gamble, J., et al (2017). The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells. Molecular Biology of the Cell, 28(8), 1066-1078.
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Wang, X., Holz, L., Chowdhury, S., Cordoba, S., Evans, K., Gall, M., Vieira de Ribeiro, A., Zheng, Y., Levy, M., Yu, M., Yao, T., Polak, N., Jolly, C., Bertolino, P., McCaughan, G., Gorrell, M. (2017). The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury. Immunology and Cell Biology, 95(5), 443-453.
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Sierro, F., Evrard, M., Rizzetto, S., Melino, M., Mitchell, A., Florido, M., Beattie, L., Walters, S., Tay, S., Lu, B., Roediger, B., Wong, Y., Warren, A., Ritchie, W., McGuffog, C., Weninger, W., Le Couteur, D., Britton, W., Saunders, B., McCaughan, G., Bowen, D., Bertolino, P., et al (2017). A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment. Immunity, 47(2), 374-388
