Robert Vandenberg
Professor
Pharmacology
University of Sydney
Australia
Biography
Dr. Robert Vandenberg is a Professor of Pharmacology, School of Medical Sciences Bosch Institute.
Research Interest
Professor Vandenberg's research interests have focused on understanding how neurotransmitter transporters work. These proteins play key roles in regulating neurotransmission in the brain and are also the targets of a number of theraputic drugs and drugs of abuse. The laboratory uses a number of state-of-the-art molecular and biophysical techniques to address questions as to how these proteins bind neurotransmitters, how drugs interact with and modulate transporters and how these processes go wrong in disease states, such as Chronic Pain, Schizophrenia and Ischemia following a stroke.
Publications
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McIlwain, B., Vandenberg, R., Ryan, R. (2016). Characterization of the Inward- and Outward-Facing Substrate Binding Sites of the Prokaryotic Aspartate Transporter, GltPh. Biochemistry, 55(49), 6801-6810.
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Vandenberg, R., Ryan, R., Br�, S. (2016). Brain transporters: From genes and genetic disorders to function and drug discovery. Neurochemistry International, 98, 1-3
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Krycer, J., Fazakerley, D., Cater, R., Thomas, K., Naghiloo, S., Burchfield, J., Humphrey, S., Vandenberg, R., Ryan, R., James, D. (2017). The amino acid transporter SLC1A3 is plasma membrane-localised in adipocytes and its activity is insensitive to insulin. FEBS Letters, 591(2), 322-330
