Sonia Saad
Professor
Medicine
University of Sydney
Australia
Biography
Dr Saad's research interest is in progressive renal disease and metabolic disease. She has published extensively in the area. She has successfully supervised 7 PhDs, 6 MSc, 1 Honours, and 2 summer students to completion and is currently supervising 3 PhD students affiliated with the University of Sydney and 1 PhD students affiliated with the University of Technology Sydney. She has expertise in diabetic kidney disease, fibrosis, oxidative stress, mitochondrial function and mitochondrial DNA quantitation. Her current work examines the effect of maternal influences including obesity and smoking on offspring predisposition to kidney disease, epigenetic regulation in disease development and novel therapies for glycaemic control and renal fibrosis.
Research Interest
In the area of metabolic disease and microvascular/ macrovascular complications of diabetes, including nephropathy and endothelial dysfunction and maternal programming and its effect on offspring predisposition to chronic kidney disease.
Publications
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Glastras, S., Chen, H., Tsang, M., Teh, R., McGrath, R., Zaky, A., Chen, J., Wong, M., Pollock, C., Saad, S. (2017). The renal consequences of maternal obesity in offspring are overwhelmed by postnatal high fat diet. PloS One, 12(2), 1-17
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Chan, Y., Saad, S., Al-Odat, I., Oliver, B., Pollock, C., Jones, N., Chen, H. (2017). Maternal L-carnitine supplementation improves brain health in offspring from cigarette smoke exposed mothers. Frontiers in Molecular Neuroscience, 10, 1-15
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Nguyen, L., Saad, S., Tan, Y., Pollock, C., Chen, H. (2017). Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus. Journal of Molecular Endocrinology, 59, 81-92