Warwick Britton
Professor of Immunology
Immunology
University of Sydney
Australia
Biography
Professor Warwick Britton AO FAHMS is Bosch Professor of Medicine and Professor of Immunology at the University of Sydney, head of the Tuberculosis Research Program at the Centenary Institute, and Research Director for Sydney Local Health District. He has longstanding interests in the immunology of mycobacterial infections and the control of tuberculosis and leprosy, including the development of novel vaccines and drugs against TB. Previously he established the Mycobacterial Research Laboratory at Anandaban Leprosy Hospital, Kathmandu, to facilitate studies to improve the management of leprosy. Currently he is CIA on the NHMRC-funded Centre for Research Excellence in Tuberculosis Control: from Discovery to Public Health Policy and Practice. This Centre includes research collaborations on the role of active case finding and community screening for tuberculosis in Vietnam, host susceptibility to tuberculosis infection, mycobacterial epidemiology and drug resistance, and the development of more effective tools to aid tuberculosis control.
Research Interest
Professor Britton is the Head of the Discipline of Infectious Diseases & Immunology and the Tuberculosis Research Program in the Centenary Institute of Cancer Medicine & Cell Biology, where he studies the immunological control of tuberculosis and new vaccine strategies to control this major human infection. He also is involved in the development and evaluation of new anti-TB drugs in collaboration with Professor Richard Payne (School of Chemistry) and new approaches to the pulmonary delivery of anti-TB drugsin collaboration with Professor Kim Chan (Faculty of Pharmacy).
Publications
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Parumasivam, T., Ashhurst (was Tyne), A., Nagalingam, G., Britton, W., Chan, H. (2017). Inhalation of Respirable Crystalline Rifapentine Particles Induces Pulmonary Inflammation. Molecular Pharmaceutics, 14(1), 328-335
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Morales, S., Britton, W., Kutter, E., Chan, H. (2017). Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders. International Journal of Pharmaceutics, 521(1-2), 141-149.
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Sierro, F., Evrard, M., Rizzetto, S., Melino, M., Mitchell, A., Florido, M., Beattie, L., Walters, S., Tay, S., Lu, B., Roediger, B., Wong, Y., Warren, A., Ritchie, W., McGuffog, C., Weninger, W., Le Couteur, D., Britton, W., Saunders, B., McCaughan, G., Bowen, D., Bertolino, P., et al (2017). A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment. Immunity, 47(2), 374-388