Derek Choi-lundberg
Senior Lecturer
Department of health
University of Tasmania
Australia
Biography
Before joining the University of Tasmania in 2000, Derek was a post-doctoral fellow in the Neuroscience Department of Genentech (South San Francisco, CA, USA), where he researched the functions of the glial cell line-derived neurotrophic factor (GDNF) family of neurotrophic factors and a-synuclein in the rodent nigrostriatal dopaminergic system. Derek's PhD from the Department of Neurobiology & Anatomy of the University of Rochester (NY, USA) was on the potential of gene therapy delivery of neurotrophic factors (specifically GDNF) for the treatment of Parkinson Disease, studied in animal models.
Research Interest
Gross anatomy, neuroanatomy, prenatal development, introductory physiology, histology (microscopic anatomy).
Publications
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Choi-Lundberg DL, Lin Q, Schallert T, Crippens D, Davidson BL, Chang YN, Chiang YL, Qian J, Bardwaj L, Bohn MC. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor. Experimental neurology. 1998 Dec 31;154(2):261-75.
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Choi-Lundberg DL, Bohn MC. Ontogeny and distribution of glial cell line-derived neurotrophic factor (GDNF) mRNA in rat. Developmental brain research. 1995 Mar 16;85(1):80-8.
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Choi-Lundberg DL, Lin Q, Chang YN, Chiang YL, Hay CM, Mohajeri H, Davidson BL, Bohn MC. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science. 1997 Feb 7;275(5301):838-41.
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Abeliovich A, Schmitz Y, Fariñas I, Choi-Lundberg D, Ho WH, Castillo PE, Shinsky N, Verdugo JM, Armanini M, Ryan A, Hynes M. Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron. 2000 Jan 31;25(1):239-52.
