Dr. Helmut Klocker
Professor
Urology
Innsbruck Medical University
Austria
Biography
Dr. Helmut Klocker is currently serving as the Professor in Department of Urology from Medical University of Innsbruck. Research Laboratory of the Department of Urology (Urologielabor) Positioned at the connection of basic and translational research and patient-oriented research and service Analysis of hormones and tumor markers Prostate cancer early detection program (Tyrolean PSA Screening Project) National (FWF) and international (EU) research projects with a focus on molecular biology of prostatic diseases Certified according to the quality management standard ISO 9001 Teaching Tumor marker and their clinical use DNA damage and DNA repair mechanism Tumor metastasis and angiogenesis Molecular biology of the prostate and prostatic diseases Courses: Hormone and tumor marker analysis in a clinical laboratory, DNA sequencing
Research Interest
Mechanism of development of therapy-resistance in prostate cancer and the role of the androgen receptor, Mechanism of androgen signaling in the male genitourinary tract, Role of growth factors, steroids and steroid modulators on gene expression in the prostate and in proliferative disorders of the prostate, Tumor markers and screening for urological malignancies
Publications
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Shi X, Peng Y, Du X, Liu H, Klocker H, Lin Q, Shi J, Zhang J. Estradiol promotes epithelialâ€toâ€mesenchymal transition in human benign prostatic epithelial cells. The Prostate. 2017 Aug 29.
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Eder T, Weber A, Neuwirt H, Grünbacher G, Ploner C, Klocker H, Sampson N, Eder IE. Cancer-associated fibroblasts modify the response of prostate cancer cells to androgen and anti-androgens in three-dimensional spheroid culture. International journal of molecular sciences. 2016 Sep 1;17(9):1458.
