Dr. Lukas A. Huber
Professor
Cell Biology
Innsbruck Medical University
Austria
Biography
I studied medicine at the University of Innsbruck. I joined the laboratory of Kai Simons at EMBL in Heidelberg (Germany) as postdoc in epithelial biology until 1994. I then moved to the University of Geneva (Switzerland) and worked in the laboratory of Jean Gruenberg on endocytosis in epithelial cells. In 1996 I started my own laboratory at the I.M.P. in Vienna (Austria) and in 2002 I got appointed as professor and head of the Division of Cell Biology and scientific director of the Biocenter of Innsbruck Medical University (Austria). My research interests have expanded to understanding the spatial and temporal resolution of signaling mechanisms mammalian cells applying molecular cell biology, mouse genetics and functional proteomics. I initiated and coordinate the FP6 EU program GROWTHSTOP, the Austrian Proteomics Platform of the Austrian Genome Program (GEN-AU), a special research program in Innsbruck entitled “Cell proliferation and Cell Death in Tumors – SFB021” of the Austrian Science Fund (FWF) and actively participatee in several EU programs. Since 2009 I am also CSO of the ONCOTYROL center of personalized cancer medicine in Innsbruck, Austria and since 2012 founder and scientific director of the Austrian Drug Screening Institute (ADSI).
Research Interest
Spatio-temporal regulation of signal transduction through scaffold complexes and their subcellular localization, proteomics, mouse genetics, translational cancer research
Publications
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Janecke AR, Xu R, Steichen‐Gersdorf E, Waldegger S, Entenmann A, Giner T, Krainer I, Huber LA, Hess MW, Frishberg Y, Barash H. Deficiency of the sphingosine‐1‐phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. Human Mutation. 2017 Apr 1;38(4):365-72.
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Huber LA. New Mouse Models for Microvillus Inclusion Disease (MVID): Where Do the Inclusions Come From and Are They Cause or Consequence?. Cellular and Molecular Gastroenterology and Hepatology. 2016 Mar;2(2):112.
