Dr. Lukas A. Huber
Professor
Biology
Innsbruck Medical University
Austria
Biography
I studied medicine at the University of Innsbruck. I joined the laboratory of Kai Simons at EMBL in Heidelberg (Germany) as postdoc in epithelial biology until 1994. I then moved to the University of Geneva (Switzerland) and worked in the laboratory of Jean Gruenberg on endocytosis in epithelial cells. In 1996 I started my own laboratory at the I.M.P. in Vienna (Austria) and in 2002 I got appointed as professor and head of the Division of Cell Biology and in 2005 as scientific director of the Biocenter of Innsbruck Medical University (Austria). I initiated and coordinated the FP6 EU program GROWTHSTOP, the Austrian Proteomics Platform of the Austrian Genome Program (GEN-AU), a special research program in Innsbruck entitled “Cell proliferation and Cell Death in Tumors” – SFB021 of the Austrian Science Fund (FWF) and actively participate in several EU programs and also coordinate programs. Since 2009 I am also CSO of the ONCOTYROL center of personalized cancer medicine in Innsbruck, Austria and since 2012 founder and scientific director of the Austrian Drug Screening Institute (ADSI).
Research Interest
Spatio-temporal regulation of signal transduction through scaffold complexes and their subcellular localization, protein transport and sorting, proteomics, mouse genetics, translational cancer research, enteropathies, lysosomal diseases, orphan diseases, drug development
Publications
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Vogel GF, Hess MW, Pfaller K, Huber LA, Janecke AR, Müller T. Towards understanding microvillus inclusion disease. Molecular and cellular pediatrics. 2016 Dec 1;3(1):3.
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Lammirato A, Patsch K, Feiereisen F, Maly K, Nofziger C, Paulmichl M, Hackl H, Trajanoski Z, Valovka T, Huber LA, Vietor I. TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation. BMC biology. 2016 Oct 25;14(1):95.
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Reintjes A, Fuchs JE, Kremser L, Lindner HH, Liedl KR, Huber LA, Valovka T. Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response. Proceedings of the National Academy of Sciences. 2016 Apr 19;113(16):4326-31.
