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Bioinformatics & Systems Biology

Bioinformatics & Systems Biology Experts

Dr. Zlatko Trajanoski

Innsbruck Medical University


Zlatko Trajanoski is a professor for bioinformatics at the Division of Bioinformatics, Biocenter, Medical University of Innsbruck, Austria. Research in his laboratory focuses on deciphering tumour–immune cell interaction using computational approaches and developing analytical tools for precision immune-oncology. His work was instrumental for the elucidation of the role of the adaptive immune system in human colorectal cancer and has led to the development of a novel immune score for the stratification of patients. His recent work focuses on the identification of mechanisms of intrinsic and acquired resistance to immunotherapy in colorectal cancer using combined experimental/computational approaches.

Research Interest

Bioinformatics and computational biology, mathematical modeling, transcriptional regulation, cancer immunology, tumor-immune cell interaction


  • Lammirato A, Patsch K, Feiereisen F, Maly K, Nofziger C, Paulmichl M, Hackl H, Trajanoski Z, Valovka T, Huber LA, Vietor I. TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation. BMC biology. 2016 Oct 25;14(1):95.

  • Willi M, Yoo KH, Wang C, Trajanoski Z, Hennighausen L. Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation. Nucleic acids research. 2016 Sep 30;44(21):10277-91.

  • Hackl H, Charoentong P, Finotello F, Trajanoski Z. Computational genomics tools for dissecting tumour-immune cell interactions. Nature Reviews Genetics. 2016 Aug 1;17(8):441-58.

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