Dr. Ines Araujo

Biography

2011            PI, “iCALP-Identification of the physiological roles of calpains in the control of cell proliferation and migration in the CNS", FCT 2005            Medal of Honour L´Oréal Portugal for Women in Science 2004            Postdoc Fellowship, Portuguese Science and Technology Foundation 2003            Short-Term Fellowship, FEBS 2000            Ph.D. Fellowship, Portuguese Science and Technology Foundation

Research Interest

Brain injury is characterized by neuronal loss and dysfunction, accompanied by neuroinflammation and an upregulation of the formation of new neurons (neurogenesis). Nevertheless, the phenomena of Injury-induced neurogenesis is far from being efficient. In our group, we are interested in understanding how the inflammatory microenvironment of the brain regulates the neurogenic response. Establishing the mechanisms by which inflammatory factors influence the formation of new neurons after injury will help in the identification of new strategies to repair the damaged brain. Adult neurogenesis Stem cells Brain repair Neuroinflammation Glutamate receptor-mediated excitotoxcity in the hippomcampus Proteases involved in neurotoxicity In Vitro and In Vivo models for neurodegeneration Brain ischemia Laser scanning microscopy Time-lapse imaging (intracellular recordings and cellular migration) CNS histology Primary cell cultures (hippocampal neurons, retinal cells, subventricular zone cells, astrocytes, microglia)