Yan Qu

Biography

Qu received her PhD and MS degree from Case Western Reserve University. She worked in Dr. Michael Weiss’s lab studying the sex-determining region Y protein (SRY), a transcription factor, and the function of its nuclear localization domain in the context of sex-related disorders. Dr. Qu continued pursuing her PhD in pharmacology department in Dr. George Dubyak’s lab. Trained as a cell biologist, her thesis focused on studying the purinergic receptor (P2X7R, an ATP receptor) signaling cascade, P2X7R mediated IL-1β processing and secretion through membrane trafficking / secretory pathway regulation and how this affects antigen presenting cells activation in the context of inflammation. Yan Qu is a Senior Principal Scientist at Rinat, which is part of the Oncology Research and Development Group. Since joining Pfizer in 2013, she has been supporting avelumab preclinical research work through collaboration with the Pfizer global development team.

Research Interest

Qu has been exploring therapeutic strategies targeting myeloid populations and designing the next generation antiCD40 Ab and cytokine fusion protein