Mohammad Moshahid Khan

Biography

Currently I am working as Research Scientist in the Department of Neurology at University of Iowa, Iowa, USA. I did my B.Sc. (Chemistry) in 2003, M.Sc. (Organic Chemistry) in 2005 from Aligarh Muslim University and Ph.D. (Toxicology) in 2009 from the department of Toxicology, Hamdard University, Delhi, India. After completion of my Ph.D. program, I have joined the Department of Internal medicine as postdoctoral Research Associate. Here I focused my research on understanding the role of plasma glycoprotein von Willebrand factor (VWF) and VWF-cleaving protease ADAMTS13 in animal model of stroke. After that I joined the department of Neurology as an Associate Scientist. Here my research investigates the molecular mechanisms that regulate inflammation in the central nervous system that are critical to our understanding of a broad spectrum of neurodegenerative diseases, including Parkinson’s disease, stroke, Alzheimer’s disease, multiple sclerosis and traumatic brain injury. I am the member of several international societies and enlisted in the Editorial board of the journal.I have published almost 40 peer reviewed original research publications and almost 50 abstracts in National and International Neuroscience-related meeting and conferences. Currently I am working as Research Scientist in the Department of Neurology at University of Iowa, Iowa, USA. I did my B.Sc. (Chemistry) in 2003, M.Sc. (Organic Chemistry) in 2005 from Aligarh Muslim University and Ph.D. (Toxicology) in 2009 from the department of Toxicology, Hamdard University, Delhi, India. After completion of my Ph.D. program, I have joined the Department of Internal medicine as postdoctoral Research Associate. Here I focused my research on understanding the role of plasma glycoprotein von Willebrand factor (VWF) and VWF-cleaving protease ADAMTS13 in animal model of stroke. After that I joined the department of Neurology as an Associate Scientist. Here my research investigates the molecular mechanisms that regulate inflammation in the central nervous system that are critical to our understanding of a broad spectrum of neurodegenerative diseases, including Parkinson’s disease, stroke, Alzheimer’s disease, multiple sclerosis and traumatic brain injury. I am the member of several international societies and enlisted in the Editorial board of the journal.I have published almost 40 peer reviewed original research publications and almost 50 abstracts in National and International Neuroscience-related meeting and conferences.

Research Interest

Neuroinflammation and neurodegeneration in Parkinson’s Disease Neuronal Stem Cells Molecular pathogenesis Oxidative stress in neuropathogenesis Neurobehavioral alterations in neurodegeneration Antioxidants and neuroprotection Cellular and molecular biology of CNS proteins Apoptosis Neuroinflammation in multiple sclerosis and stroke Neuroinflammatory mediators in CNS SiRNA mediated down regulation of inflammatory mediators and cytokines in CNS Stress-activated protein kinases in inflammatory signal transduction Cytokines and chemokines in CNS Endothelial dysfunction, BBB disruption and immune cell mediated injury in sub-acute/ chronic phase of stroke. Brain lipids and their metabolism in neurodegeneration Thrombosis and Intravital microscopy