Charles J Malemud

Biography

Charles J. Malemud received the Ph.D. from George Washington University in 1973. He then completed postdoctoral studies in the Department of Pathology at the State University of New York at Stony Brook in 1977 where he studied the role of neutrophils in cartilage response to injury. Currently, Dr. Malemud is Professor of Medicine & Anatomy in the Division of Rheumatic Diseases and Senior Investigator in the Arthritis Research Group at Case Western Reserve University School of Medicine. I have published more than 225 papers and reviews primarily in the field of chondrocyte biology. My current research focuses on the role of chondrocyte signal transduction pathways and how these pathways regulate matrix metalloproteinase gene expression and controlled cell death. I am also involved in collaborative studies designed to determine the role played by progesterone receptors in normal parturition and pre-term birth. Professor Malemud is on the editorial board of several rheumatology, immunology and musculoskeletal journals and is Editor-in-Chief of the Journal of Clinical and Cellular Immunology and Global Vaccines and Immunology. Charles J. Malemud received the Ph.D. from George Washington University in 1973. He then completed postdoctoral studies in the Department of Pathology at the State University of New York at Stony Brook in 1977 where he studied the role of neutrophils in cartilage response to injury. Currently, Dr. Malemud is Professor of Medicine & Anatomy in the Division of Rheumatic Diseases and Senior Investigator in the Arthritis Research Group at Case Western Reserve University School of Medicine. I have published more than 225 papers and reviews primarily in the field of chondrocyte biology. My current research focuses on the role of chondrocyte signal transduction pathways and how these pathways regulate matrix metalloproteinase gene expression and controlled cell death. I am also involved in collaborative studies designed to determine the role played by progesterone receptors in normal parturition and pre-term birth. Professor Malemud is on the editorial board of several rheumatology, immunology and musculoskeletal journals and is Editor-in-Chief of the Journal of Clinical and Cellular Immunology and Global Vaccines and Immunology.

Research Interest

Biology of the Musculoskeletal System Intracellular Signal Transduction Pathways Inflammation Pro-inflammatory, Anti-Inflammatory & Anabolic Cytokines Apoptosis Matrix Metalloproteinases Osteoarthritis, Rheumatoid Arthritis, Fibromyalgia Autoimmune Disorders