Bart De Strooper
scientist
medical science
Flanders Interuniversity Institute for Biotechnology
Belgium
Biography
MD: Univ. of Leuven, Leuven, Belgium, 1985 PhD: Univ. of Leuven, Leuven, Belgium, 1992 Postdoc: EMBL, Heidelberg, Germany 1994 VIB Group leader since 1999 EMBO Member Scientific Director, Dept. of Molecular and Developmental Genetics 2007-16
Research Interest
Neuroscience
Publications
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Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models Huang Y Maruszewska A Horré K Vandewyer E Wolfs L Snellinx A Saito T Radaelli E Corthout N Colombelli J Lo A Van Aerschot L Callaerts-Vegh Z Trabzuni D Bossers K Verhaagen J Ryten M Munck S D'hooge R Swaab D Hardy J Saido T De Strooper B* Thathiah A*Science Translational Medicine, 7, 309ra164, 2015
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Familial Alzheimer's Disease Mutations in Presenilin Generate Amyloidogenic Abeta Peptide Seeds Veugelen S Saito T Saido T Chávez Gutiérrez L* De Strooper B*NEURON, 90, 410-6, 2016
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Alzheimer's-Causing Mutations Shift Abeta Length by Destabilizing gamma-Secretase-Abetan Interactions Szaruga M Munteanu B Lismont S Veugelen S Horré K Mercken M Saido T Ryan N De Vos T Savvides S Gallardo R Schymkowitz J Rousseau F Fox N Hopf C De Strooper B* Chávez Gutiérrez L*CELL, 170, 443-456 e14, 2017
