Jan Cools
scientist
medical science
Flanders Interuniversity Institute for Biotechnology
Belgium
Biography
PhD: University of Leuven, Leuven, Belgium, 2001 Postdoc.: Harvard Medical School, Boston, USA, 2001-03 VIB Group leader since 2008
Research Interest
Cancer
Publications
-
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model Degryse S, De Bock C, Cox L, Demeyer S, Gielen O, Mentens N, Jacobs K, Geerdens E, Gianfelici V, Hulselmans G, Fiers M, Aerts S, Meijerink J, Tousseyn T, Cools JBLOOD, 124, 3092-100, 2014
-
Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia Vicente C Schwab C Broux M Geerdens E Degryse S Demeyer S Lahortiga I Elliott A Chilton L La Starza R Mecucci C Vandenberghe P Goulden N Vora A Moorman A Soulier J Harrison C* Clappier E* Cools J*HAEMATOLOGICA, 100, 1301-10, 2015
-
Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, Gielen O, Vicente C, Vandepoel R, Geerdens E, Uyttebroeck A, Boeckx N, De Bock C, Cools JBLOOD, 128, 2642-2654, 2016
