Sarah-maria Fendt
scientist
medical science
Flanders Interuniversity Institute for Biotechnology
Belgium
Biography
PhD: ETH Zurich, Institute of Molecular Systems Biology, 2009 Postdoctoral Fellow: Harvard Medical School, Boston, 2010 Postdoctoral Fellow: Massachusetts Institute of Technology , Cambridge, 2011-2012 VIB Group leader since 2013
Research Interest
Cancer Systems biology
Publications
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Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis Christen S, Lorendeau D, Schmieder R, Broekaert D, Metzger K, Veys K, Elia I, Buescher J, Orth M, Davidson S, Grünewald T, De Bock K, Fendt SCell Reports, 17, 837-848, 2016
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Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors Lorendeau D, Rinaldi G, Boon R, Spincemaille P, Metzger K, Jäger C, Christen S, Dong X, Kuenen S, Voordeckers K, Verstreken P, Cassiman D, Vermeersch P, Verfaillie C, Hiller K, Fendt SMETABOLIC ENGINEERING, e-pub, e-pub, 2017
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Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells Elia I, Broekaert D, Christen S, Boon R, Radaelli E, Orth M, Verfaillie C, Grünewald T, Fendt SNature Communications, 8, 15267, 2017
