Wim Annaert
scientist
medical science
Flanders Interuniversity Institute for Biotechnology
Belgium
Biography
PhD: Univ. of Antwerp, Antwerp, Belgium, 1993 Postdoc: Yale Univ., Connecticut, USA, 1994-96 VIB Group leader since 2001
Research Interest
Neuroscience Cell biology
Publications
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Lysosomal calcium homeostasis defects, not proton pump defects, cause endo-lysosomal dysfunction in PSEN-deficient cells Coen K, Flannagan R, Baron S, Carraro-Lacroix L, Wang D, Vermeire W, Michiels C, Munck S, Baert V, Sugita S, Wuytack F, Hiesinger P, Grinstein S, Annaert WJOURNAL OF CELL BIOLOGY, 198, 23-35, 2012
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Rer1p maintains ciliary length and signaling by regulating gamma-secretase activity and Foxj1a levels Jurisch N* Rose A* Lu H Raemaekers T Munck S Baatsen P Baert V Vermeire W Scales S Verleyen D Vandepoel R Tylzanowski P Yaksi E De Ravel T Yost H Froyen G Arrington C Annaert WJOURNAL OF CELL BIOLOGY, 200, 709-20, 2013
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Restricted Location of PSEN2/gamma-Secretase Determines Substrate Specificity and Generates an Intracellular Abeta Pool Sannerud R, Esselens C, Ejsmont P, Mattera R, Rochin L, Tharkeshwar A, De Baets G, De Wever V, Habets R, Baert V, Vermeire W, Michiels C, Groot A, Wouters R, Dillen K, Vints K, Baatsen P, Munck S, Derua R, Waelkens E, Basi G, Mercken M, Vooijs M, Bollen M, Schymkowitz J, Rousseau F, Bonifacino J, Van Niel G, De Strooper B, Annaert WCELL, 166, 193-208, 2016