Walter Luis Garrido Cavalcante
Professor
Pharmacology DepartmentÂ
University of Minas
Brazil
Biography
He graduated in Biological Sciences (2002) from the Paulista State University Júlio de Mesquita Filho. He completed his Masters (2005) and PhD (2009) in Pharmacology from the Paulista State University Júlio de Mesquita Filho. He has two postdoctoral degrees in the country by the Paulista State University and another abroad by the University of Porto (financed by FAPESP, laboratory of Pharmacology and Neurobiology of the Institute of Biomedical Sciences Abel Salazar). He is currently Adjunct Professor A of the Federal University of Minas Gerais in the Department of Pharmacology. Has experience in the field of Pharmacology, with emphasis in Pharmacology of Neuromuscular Junction, acting mainly on the following topics: ophidian toxins and exercise physiology. He was professor for five years of the Faculty of Social and Agrarian Sciences of Itapeva, mainly ministering the disciplines of Biochemistry, Physiology and Pharmacology, and for a semester at the State University of São Paulo, ministering the discipline of Pharmacology. He is currently an Adjunct Professor at the Department of Pharmacology at UFMG. It works mainly on the following topics: neuromuscular junction and toxinology.
Research Interest
Pharmacology of Neuromuscular Junction, Physiology of Physical Effort, Biochemical and Molecular Pharmacology, Biochemistry and Molecular, Pharmacology of Neuromuscular Junction, Toxinologia, Pharmacology of Neuromuscular Junction and Toxinology.
Publications
-
Oliveira L, Costa AC, Noronha-Matos JB, Silva I, Cavalcante WL, Timóteo MA, Corrado AP, Dal Belo CA, Ambiel CR, Alves-do-Prado W, Correia-de-Sá P. Amplification of neuromuscular transmission by methylprednisolone involves activation of presynaptic facilitatory adenosine A 2A receptors and redistribution of synaptic vesicles. Neuropharmacology. 2015 Feb 28;89:64-76.
-
Cavalcante WL, Noronha-Matos JB, Timóteo MA, de Mattos Fontes MR, Gallacci M, Correia-de-Sá P. Neuromuscular paralysis by the basic phospholipase A 2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage. Toxicology and Applied Pharmacology. 2017 Sep 1.
-
Fernandes CA, Pazin WM, Dreyer TR, Bicev RN, Cavalcante WL, Fortes-Dias CL, Ito AS, Oliveira CL, Fernandez RM, Fontes MR. Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism. Scientific Reports. 2017;7.
