Sridhar Narayan
Board member, independent
Pharmaceutical
Applied BioCode, Inc.
Canada
Biography
Dr. Narayan has spent over 9 years in large pharmaceutical companies. As a medicinal chemistry project leader at AstraZeneca and Eisai, Dr. Narayan successfully led teams working on various drug-discovery programs ranging from hit identification and lead optimization through candidate nomination and IND filing. He led the chemistry team on the discovery of a first in class TLR7 antagonist for the treatment of lupus. Due to his experience in the pharmaceutical industry, Dr. Narayan is intimately familiar with the process of optimizing pharmacokinetics, metabolism, toxicity and other parameters of candidate compounds, as well as managing external research at CROs. Dr. Narayan joined Navitor Pharmaceuticals as the Director of Medicinal Chemistry in July 2015, where he is leading multiple projects on the discovery of small molecule modulators of the mTOR pathway for the treatment of metabolic diseases. Dr. Narayan is also advisor for Appili on aspects of the API-1503 program including medicinal chemistry, primary and secondary assays, X-ray crystallography and computer-aided drug design. Dr. Narayan has spent over 9 years in large pharmaceutical companies. As a medicinal chemistry project leader at AstraZeneca and Eisai, Dr. Narayan successfully led teams working on various drug-discovery programs ranging from hit identification and lead optimization through candidate nomination and IND filing. He led the chemistry team on the discovery of a first in class TLR7 antagonist for the treatment of lupus. Due to his experience in the pharmaceutical industry, Dr. Narayan is intimately familiar with the process of optimizing pharmacokinetics, metabolism, toxicity and other parameters of candidate compounds, as well as managing external research at CROs. Dr. Narayan joined Navitor Pharmaceuticals as the Director of Medicinal Chemistry in July 2015, where he is leading multiple projects on the discovery of small molecule modulators of the mTOR pathway for the treatment of metabolic diseases. Dr. Narayan is also advisor for Appili on aspects of the API-1503 program including medicinal chemistry, primary and secondary assays, X-ray crystallography and computer-aided drug design.
Research Interest
Clinical Pharmacy Pharmaceutical Administration Medicinal Chemistry
