Caley is a managing director of KVP. He has invested in Aspreva, Boreal, CoTherix, CVRx, Kai, Rib-X, QuatRx, and ViewRay, and is currently a board member of Boreal and ViewRay. Prior to becoming a venture capitalist in 2000, Caley received his M.D. from the University of California, San Francisco. During medical school, he ran a research program investigating the genetic causes of deafness and the application of gene therapy to treatment of hearing loss. The findings were published in leading journals including Nature Genetics. After medical school, Caley completed a general surgery internship at the University of California, San Francisco. He received an A.B. magna cum laude from Harvard College.