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Alan Castle

Professor
Biological Sciences
Brock University
Canada

Biography

Dr. Alan Castle is affiliated to Biological Sciences, Brock University, where Dr. Alan Castle is currently working as Professor. Dr. Alan Castle has authored and co-authored several national and international publications and also working as a reviewer for reputed professional journals. Dr. Alan Castle is having an active association with different societies and academies around the world. Dr. Alan Castle made his mark in the scientific community with the contributions and widely recognition from honourable subject experts around the world. Dr. Alan Castle has received several awards for the contributions to the scientific community. Dr. Alan Castle major research interest involves Confrontation between fungal cells of the same species or different species leads to one of a variety of events including no apparent interaction, avoidance, growth inhibition, death of one or both fungi, or cell fusion (parasitic, vegetative or sexual fusion). Early cellular recognition events are mediated by production and reception of diffusible signals or through direct cell to cell contact mediated by surface ligands and receptors. My research is devoted to two systems chosen for the elucidation of these early events. Longer term goals include definition of the genetic control of signal production, reception and transduction and determination of the universality of these mechanisms within other fungus-fungus interactions. Work of this nature will give insight into diverse areas such as recognition, attachment and disease progression in plant and animal tissues by parasitic fungi and the use of fungi as biocontrol agents of other fungi..

Research Interest

Confrontation between fungal cells of the same species or different species leads to one of a variety of events including no apparent interaction, avoidance, growth inhibition, death of one or both fungi, or cell fusion (parasitic, vegetative or sexual fusion). Early cellular recognition events are mediated by production and reception of diffusible signals or through direct cell to cell contact mediated by surface ligands and receptors. My research is devoted to two systems chosen for the elucidation of these early events. Longer term goals include definition of the genetic control of signal production, reception and transduction and determination of the universality of these mechanisms within other fungus-fungus interactions. Work of this nature will give insight into diverse areas such as recognition, attachment and disease progression in plant and animal tissues by parasitic fungi and the use of fungi as biocontrol agents of other fungi.

Publications

  • Castle, A. J., D. Speranzini, N. Rghei., G. Alm, D. Rinker and J. Bissett. 1998. Molecular and morphological identification of Trichoderma isolates causing losses on North American mushroom farms. Appl. Environ. Microbiol. 64:133-137.

  • Horgen, P. A. and A. J. Castle. 1999. Genetically engineered mushrooms, are they a blessing or bad news? Mushroom News.

  • Svircev, A. M., J. Gill, T. Zhou, A. Castle and M. Chiba. 2000. A comparison of techniques for assessing benzimidazole resistance in Venturia inaequalis. J. Phytopathol. 148: 205-210.

  • Horgen, P. A. and A. Castle. 2002. The application and potential of molecular approaches to mushrooms. The Mycota (in press).

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