Brian D. Roy
Professor
Kinesiology
Brock University
Canada
Biography
I am interested in the regulation of integrated physiological responses and muscle metabolism during physical activity and dietary manipulations. My current work is focused on the impact of alterations in muscle cell volume on the regulation of muscle metabolism and muscle hypertrophy and atrophy. I am also interested in the effects of dietary supplementation of various compounds, including dairy products, on muscle and bone metabolism in healthy, diseased, and ageing populations. I am also currently investigating dietary interventions for the treatment and reduction in severity of sport induced concusssions.
Research Interest
Integrated metabolic responses to exercise and nutrition; Protein metabolism; Interaction of dietary intake of dairy products and physical activity; Dietary interventions for sport induced concussions
Publications
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Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation Rebecca E. K. MacPherson*, Rene Vandenboom, Brian D. Roy, Sandra J. Peters. Physiol Rep, 1 (4), 2013, e00084.
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Maternal high fat feeding does not have long-lasting effects on body composition and bone health in female and male rat offspring at young adulthood. Paula Miotto, Laura Castelli, Foyinsola Amoye, Paul LeBlanc, Sandra Peters, Brian Roy, Wendy Ward. Molecules. 2013, 18(12), 15094-15109
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Pyruvate Dehydrogenase Kinase-4 Contributes to the Recirculation of Gluconeogenic Precursors During Post-Exercise Glycogen Recovery. Eric Herbst, Rebecca MacPherson, Paul LeBlanc, Brian Roy, Nam Ho Jeoung, Robert Harris, and Sandra Peters. Am J Physiol Regul Integr Comp Physiol. 2013 Dec 4. [Epub ahead of print]6.
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A School-Based Type 2 Diabetes Prevention Program for Canadian Elementary Students. Lindsey Cline, James Mandigo, Panagiota Klentrou, Brian Roy. PHEnex J. Vol. 6, No. 3, 2014.
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Elevated concentrations of circulating cytokines and correlations with nerve conduction velocity in human peripheral nerves. Allison DJ, Green LA, Gabriel DA, Roy BD, Inglis JG, Ditor DS. J Neuroimmunol. 2014 Dec 15;277(1-2):134-9.
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A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. MacPherson RE, Castelli LM, Miotto PM, Frendo-Cumbo S, Milburn A, Roy BD, LeBlanc PJ, Ward WE, Peters SJ. Lipids. 2015 Feb;50(2):205-17.
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Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein (G0S2) expression in male Sprague-Dawley rat skeletal muscle compared to relative content of adipose triglyceride lipase (ATGL) and comparitive gene identification-58 (CGI-58). Turnbull PC, Ramos SV, MacPherson RE, Roy BD, Peters SJ. PLoS One. 2015 Mar 26;10(3):e0120136.
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Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles. Turnbull PC, Longo AB, Ramos SV, Roy BD, Ward WE, Peters SJ. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15;310(2):R125-33.