Jens R. Coorssen
Professor
Health Sciences
Brock University
Canada
Biography
Jens trained in Canada (BSc and MSc at Brock; PhD at McMaster), the Max Planck Institute for Medical Research (Heidelberg) and the National Institutes of Health (USA). As an Associate Professor, Faculty of Medicine and Hotchkiss Brain Institute, U. Calgary, he was recruited to the new School of Medicine, U. Western Sydney as Foundation Professor & Chair of Molecular Physiology, and established the UWS Molecular Medicine Research Group. He came ‘home’ to Brock in 2016. His quantitative, transdisciplinary research focuses on understanding molecular mechanisms.
Research Interest
Proteomics; Lipidomics; Biomarkers; Molecular Mechanisms
Publications
-
Abbineni, P., Wright, E.P., Rogasevskaia, T.P., Killingsworth, M., Malladi, C., and Coorssen, J.R. (2014) The Sea Urchin Egg and Cortical Vesicles as Model Systems to Dissect the Fast, Ca2+-Triggered Steps of Regulated Exocytosis. In: Neuromethods (Thorn, P., Ed). Humana Press / Springer.
-
Stimpson, S.E., Coorssen, J.R.*, and Myers, S.J.* (2015) Mitochondrial protein alterations in a familial peripheral neuropathy caused by the V144D amino acid mutation in the sphingolipid protein, SPTLC1. J. Chem. Biol. 8, 25-35.
-
Stimpson, S.E., Coorssen, J.R.*, and Myers, S.J.* (2015) Optimal isolation of mitochondria for proteomic analyses. Analytical Biochem. 475, 1-3.
-
Mahadeo, M., Furber, K.L., Lam, S., Coorssen, J.R.*, and Prenner, E.J.* (2015) Secretory vesicle cholesterol: correlating lipid domain organization and Ca2+ triggered fusion. BBA (Biomembranes) 1848, 1165-1174.
-
Partridge, M.A., Myers, S.J., Gopinath, S., and Coorssen, J.R. (2015) Proteomics of a conundrum: thoughts on addressing the aetiology vs. progression of Multiple Sclerosis. Proteomics Clinical Applications 9, 838-843.
-
Rogasevskaia, T. and Coorssen, J.R. (2015) The role of phospholipase D in regulated exocytosis. J. Biol. Chem. 290, 28683–28696.
-
Coorssen, J.R. and Yergey, A.L. (2015) Proteomics is analytical chemistry: Fitness-for-purpose in top-down and bottom-up analyses. Proteomes 3, 440-453.
-
Stimpson, S.E., Coorssen, J.R.*, and Myers, S.J.* (2015) Proteome alterations associated with the V144D SPTLC1 mutation that causes Hereditary Sensory Neuropathy-1. Electronic J. Biol. 11, 176-186.
-
Partridge, M.A., Gopinath, S., Myers, S.J., and Coorssen, J.R. (2016) An initial top-down proteomic analysis of the standard cuprizone mouse model of Multiple Sclerosis. J. Chem. Biol. 9, 9-18.
-
Stimpson, S.E., Lauto, A., Coorssen, J.R.*, and Myers, S.J.* (2016) Isolation and identification of ER associated proteins with unique expression changes specific to the V144D SPTLC1 mutations in HSN-I. Biochem. Analytical Biochem. 5(1), 248.
