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Physicaltherapy & Rehabilitation Experts

Sandra Peters

Professor
Kinesiology
Brock University
Canada

Biography

My research program seeks to understand the regulation of muscle metabolism in response to diet, exercise, and endurance training. My first research interest was focused on studying the interaction between carbohydrate and fat metabolism through the regulation of the enzyme “pyruvate dehydrogenase”. More recently, my interests have shifted to learning about the muscle “perilipin” or PLIN proteins, which coat lipid droplets and putatively regulate muscle fat metabolism. I am pleased to have strong collaborative ties, and an emerging interest in the regulation of bone metabolism.

Research Interest

Regulation of muscle metabolism; Muscle lipid droplet proteins, the perilipin family (PLINs); Regulation of muscle pyruvate dehydrogenase by diet and exercise

Publications

  • Nash, L.A., P.J. Sullivan, S.J. Peters, W.E. Ward. Rooibos flavonoids, orientin and luteolin, stimulate mineralization in human osteoblasts through the Wnt pathway. Molec Nutr Food Res 59(3): 443-453, 2015.

  • MacPherson R.E.K., L.M. Castelli, P.M. Miotto, S. Frendo-Cumbo, A. Milburn, B.D. Roy, P.J. LeBlanc, W.E. Ward, and S.J. Peters. A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. Lipids 50(2): 205-217, 2015.

  • Ramos S.V., P.C. Turnbull, R.E.K MacPherson, P.J. LeBlanc, W.E. Ward, and S.J. Peters. Changes in mitochondrial PLIN3 and PLIN5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction. Exp Physiol 100(4): 450-462, 2015.

  • Turnbull, P.C., S.V. Ramos, R.E.K. MacPherson, B.D. Roy and S.J. Peters. Characterization of lipolytic inhibitor G(0)/G(1) switch gene-2 protein expression in skeletal muscle and heart compared to relative content of ATGL and CGI-58. PLOSone 10(3): e0120136, 2015.

  • Sullivan, P., M. Gagnon, K. Gammage, and S.J. Peters. Is the effect of behavioral synchrony on cooperative behavior mediated by pain threshold? J Social Psych 155(6): 650-660, 2015.

  • Turnbull, P.C., A.B. Longo, S.V. Ramos, B.D. Roy, W.E. Ward, and S.J. Peters. Increases in skeletal muscle ATGL and its inhibitor G0S2 following 8 weeks of endurance training in metabolically different rat skeletal muscles. Am J Physiol Regul Integr Comp Physiol 310(2): R125-R133, 2016.

  • Nash, L.A., S.J. Peters, P.J. Sullivan, and W.E. Ward. Supraphysiological levels of quercetin glycosides are required to alter mineralization in Saos2 cells. Int J Environ Res Public Health 13(5): E460, 2016.

  • Bott, K.N., S.M. Sacco, P.C. Turnbull, A.B. Longo, W.E. Ward and S.J. Peters. Skeletal-site specific effects of endurance running on bone structure and strength in growing rats. Submitted to App Physiol Nutr Metab 41(6): 597-604, 2016.

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