Andrew makrigiannis
Professor
Department of Microbiology and Immunology
Dalhousie University
Canada
Biography
Dr. ANDREW MAKRIGIANNIS is affiliated to Department of Microbiology and Immunology, Dalhousie University. Dr. ANDREW MAKRIGIANNIS is currently providing services as Professor. Dr. ANDREW MAKRIGIANNIS has authored I145and co-authored multiple peer-reviewed scientific papers and presented works at many national and International conferences. Dr. ANDREW MAKRIGIANNIS contributions have acclaimed recognition from honourable subject experts around the world. Dr. ANDREW MAKRIGIANNIS is actively associated with different societies and academies. Dr. ANDREW MAKRIGIANNIS academic career is decorated with several reputed awards and funding. Dr. ANDREW MAKRIGIANNIS research interests include Dr. Makrigiannis’ research focus is the innate immune system, and in particular Natural Killer (NK) cell recognition of virally-infected or cancerous cells via the polymorphic Ly49 family of class I MHC receptors and the related NKR-P1 receptor family, in order to understand the contribution of NK cell receptors to diseases for translation into clinical therapies..
Research Interest
Dr. Makrigiannis’ research focus is the innate immune system, and in particular Natural Killer (NK) cell recognition of virally-infected or cancerous cells via the polymorphic Ly49 family of class I MHC receptors and the related NKR-P1 receptor family, in order to understand the contribution of NK cell receptors to diseases for translation into clinical therapies.
Publications
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McFall E, Tu MM, Al-Khattabi N, Tai LH, St-Laurent AS, Tsankova V, Hall CW, Belanger S, Troke AD, Wight A, Mahmoud AB, Zein HS, Rahim MM, Carlyle JR, and Makrigiannis AP. Optimized tetramer analysis reveals Ly49 promiscuity for MHC ligands. J. Immunol. 2013 Dec; 191(11):5722-9.
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Tu MM, Mahmoud AB, Wight A, Mottashed A, Bélanger S, Rahim MM, Abou-Samra E, and Makrigiannis AP. Ly49 family receptors are required for cancer immunosurveillance mediated by natural killer cells. Cancer Res. 2014 Jul; 74(14):3684-94.
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Rahim MM, Chen P, Mottashed AN, Mahmoud, AB, Thomas MJ, Zhu Q, Brooks CG, Kartsogiannis V, Gillespie MT, Carlyle JR*, and Makrigiannis AP*. The mouse NKR-P1B:Clr-b recognition system is a negative regulator of innate immune responses. Blood. 2015 Jan; 125(14):2217-27.
