Karen Bush

Biography

Dr. Bush, with a Ph.D. in biochemistry from Indiana University, began her work on β-lactamases and β-lactamase inhibitors at the Squibb Institute for Medical Research in 1977, and continued working in anti-infective research at Bristol-Myers Squibb, Lederle (now part of Pfizer), Astra Zeneca, and Johnson & Johnson until 2009.  ​   During her pharmaceutical career Dr. Bush worked on the research teams that discovered and developed aztreonam, Zosyn® (piperacillin-tazobactam), levofloxacin, doripenem, ceftobiprole, and the influenza drug peramivir. She also led a microbiology research team that was responsible for the discovery and early development of novel ketolides, oxazolidinones, and fluoroquinolones. Currently she has composed over 210 peer-reviewed publications. ​ Dr. Bush is currently an Adjunct Professor in the Biology Department and the Biochemistry Department at Indiana University where she teaches in the graduate biotechnology program. She is a Fellow of the American Academy of Microbiology, an Advisor for the Clinical and Laboratory Standards Institute, a past editor of the journal, Antimicrobial Agents & Chemotherapy, and a reviewer for many microbiology journals and NIH study sections.

Research Interest

Pharmaceutical Sciences