Andrea Leblanc
James McGill Professor
Neurology and Neurosurgery
McGill University
Canada
Biography
Andrea LeBlanc is a full professor in the Department of Neurology and Neurosurgery at McGill University and a researcher of the Bloomfield Center for Research in Aging in the Lady Davis Institute for Medical Research in Montreal. The focus of Dr LeBlanc's research is on Alzheimer and prion diseases. In Alzheimer disease, her laboratory is pursuing the identification of underlying molecular mechanisms of neuronal degeneration in pre-clinical and clinically defined Alzheimer disease brains. Her work in prion disease have resulted in the identification of mutations associated with two familial forms of prion diseases and her laboratory is presently investigating a normal anti-death function for the cellular normal prion protein in neurons, which is eliminated in familial mutants. For more information, you can visit http://www.bloomfieldcentre.org/
Research Interest
neurology
Publications
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Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element. Déry MA, LeBlanc AC.
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Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice. Pakavathkumar P, Noël A, Lecrux C, Tubeleviciute-Aydin A, Hamel E, Ahlfors JE, LeBlanc AC.
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Novel therapeutic target against Alzheimer. LeBlanc AC.
