Antonis E Koromilas
Professor
Microbiology & Immunology
McGill University
Canada
Biography
Lady Davis Institute for Medical Research, Rm 508 Sir Mortimer B. Davis-Jewish General Hospital
Research Interest
Control of protein synthesis, mRNA translation, environmental stress, tumor suppressor genes, oncogenes, signal transduction, protein phosphorylation, breast, lung and colon cancer, chemotherapeutic drugs.
Publications
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Mounir Z, Krishnamoorthy JL, Robertson GP, Scheuner D, Kaufman RJ, Georgescu MM, Koromilas AE. Tumor suppression by PTEN requires the activation of the PKR-eIF2α phosphorylation pathway. Sci Signal 2009;2:ra85.
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Koromilas AE, Mounir Z. Control of oncogenesis by eIF2α phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment. Future Oncol 2013;9:1005-15.
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Koromilas AE. Roles of the translation initiation factor eIF2α serine 51 phosphorylation in cancer formation and treatment. Biochim Biophys Acta 2015;1849:871-80.
