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Armando Jardim

Associate Professor
Parasitology
McGill University
Canada

Biography

Armando Jardim is an Associate Professor of Biochemistry at Institute of Parasitology and an Associate Member of the Department of Microbiology and Immunology at McGill University. He has more than 25 years of experience in the field of protein/peptide biochemistry, chromatographic separation techniques and molecular biology. His research program focuses on structural and functional dissection the molecular machinery required for the biogenesis of the glycosome, a subcellular organelle that is critical for the viability of the medically important protozoan parasite Leishmania. This work has led to the identification of novel proteins that are being exploited as potential drug targets. His team, in collaboration with colleagues, is investigating a spectrum of proteins and small molecule metabolites secreted by the helminth parasite Trichuris suis with the aim to identifying immunomodulatory molecules for the treatment of autoimmune disorders such as inflammatory bowel disease. He has authored 64 publications in leading edge journals and filed a number of patents which have stemmed from his research efforts. Dr. Jardim has served as the Director of the Centre for Host-Parasite Interactions, an expert reviewer for national and international funding agencies, and as an Associate Editor for the journals PLOS Neglected and Tropical Diseases and Molecular and Biochemical Parasitology.

Research Interest

The Jardim laboratory is investigating the medically important infectious organisms Leishmania and E. coli which cause leishmaniasis and gastrointestinal diseases, respectively.

Publications

  • Valanparambil RM, Segura M, Tam M, Jardim A, Geary TG and Stevenson MM (2014) Production and analysis of immunomodulatory excretory-secretory products from the mouse gastrointestinal nematode Heligmosomoides polygyrus bakeri. Nat Protoc 9: 2740-54.

  • Chatterjee A, Caballero-Franco C, Bakker D, Totten S, Jardim A. (2015) Pore-forming Activity of the Escherichia coli Type III Secretion System Protein EspD.. J Biol Chem. 290:25579-94

  • van Bergen B, Cyr N, Strasser R, Blanchette M, Sheppard JD, Jardim A. (2016) α,β-Dicarbonyl reduction is mediated by the Saccharomyces Old Yellow Enzyme. FEMS Yeast Res.

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