Cynthia Gates Goodyer
Associate Professor
Division of Endocrinology & Metabolism
McGill University
Canada
Biography
I am co-leader of a multidisciplinary research team from five Canadian universities and Health Canada that is studying the effects of brominated flame retardants (BFRs) on developmental abnormalities of male and female reproductive systems and fertility. Our team is also exploring ethical, legal and social issues surrounding the use of BFRs since they are environmental contaminants and pose a potential health risk not only to individuals, but to future generations. A second focus of my research is on human growth. The long-term goal of this program is to help in the creation of a “biological blueprint” that will allow researchers to define genetic alterations in children with abnormal growth or with metabolic disorders, including obesity and cancer. Our group is presently working to identify regions within the growth hormone receptor gene that control expression of the receptor in growth hormone target tissues, such as bone, liver and fat.
Research Interest
Human growth, gene regulation, growth hormone, growth hormone receptor, idiopathic short stature, obesity, cancer, environmental contaminants, brominated flame retardants, reproduction
Publications
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Rawn, D.F.K., Gaertner, D.W., Weber, D., Curran, I.H.A., Cooke G.M. and Goodyer, C.G. Hexabromocyclododecane concentrations in Canadian human fetal liver and placental tissues. Science of the Total Environment 468-9C: 622-629, 2014.
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Elzein, S.* and Goodyer, C.G. Regulation of human growth hormone receptor expression by microRNAs. Mol Endocrinol 28: 1448-1459, 2014.
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Poon, S., Wade, M.W., Aleksa, K., Rawn, D.F.K., Carnevale, A., Gaertner, D.W., Sadler, A., Breton, F., Koren, G., Ernest, S.R., Lalancette, C, Robaire, B., Hales, B.F. and Goodyer, C.G. Hair as a biomarker of exposure to polybrominated diphenyl ethers (PBDEs). Environ Sci Technol (in press).
