Daniel J. Bernard
Professor
Division of Endocrinology & Metabolism
McGill University
Canada
Biography
Prof. Bernard earned his Ph.D. at Johns Hopkins University and then conducted post-doctoral research in molecular endocrinology at Northwestern University. His first independent position was as a Staff Scientist at the Population Council’s Center for Biomedical Research at The Rockefeller University. He then moved his lab to McGill in April 2006.
Research Interest
The Bernard lab investigates molecular mechanisms of pituitary hormone synthesis using in vitro and in vivo approaches. Projects in the lab concern: 1) signal transduction mechanisms through which members of the transforming growth factor β superfamily regulate pituitary follicle-stimulating hormone (FSH) synthesis, 2) mechanisms of gonadotropin-releasing hormone (GnRH) signaling in pituitary gonadotrope cells, and 3) hypothalamic-pituitary control of thyroid hormone production.
Publications
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Tran S, Zhou X, Lafleur C, Calderon MJ, Ellsworth BS, Kimmins S, Boehm U, Treier M, Boerboom D, Bernard DJ (2013) Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice. Mol Endocrinol. 27(3):407-21. PMID: 23340250
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Bernard DJ, Tran S (2013) Mechanisms of activin-stimulated FSH synthesis: the story of a pig and a FOX. Biol Reprod. 88(3):78. PMID: 23426431
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Fortin J, Boehm U, Deng CX, Treier M, Bernard DJ (2014) Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.FASEB J. 28(8):3396-410. PMID: 24739304
