Dilson E. Rassier
Associate Member
Psychiatry
McGill University
Canada
Biography
McGill University
Research Interest
Research focuses on the molecular and cellular mechanisms of skeletal muscle contraction and force regulation. The general objective is to understand how muscle molecules interact and convert chemical energy into mechanical work, causing muscle contraction. To achieve this objective the laboratory uses an array of experimental preparations, including single muscle cells, isolated myofibrils and sarcomeres, and myosin/actin filaments.
Publications
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Sarcomere mechanics in striated muscles: from molecules to sarcomeres to cells. Rassier DE.
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Prolonged force depression after mechanically demanding contractions is largely independent of Ca2+ and reactive oxygen species. Kamandulis S, de Souza Leite F, Hernández A, Katz A, Brazaitis M, Bruton JD, Venckunas T, Masiulis N, Mickeviciene D, Eimantas N, Subocius A, Rassier DE, Skurvydas A, Ivarsson N, Westerblad H.
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Microfluidic perfusion shows intersarcomere dynamics within single skeletal muscle myofibrils. de Souza Leite F, Minozzo FC, Altman D, Rassier DE.