John Orlowski
professor
Department of Physiology
McGill University
Canada
Biography
Education: B.Sc., McGill, M.Sc., Ph.D., Queen's
Research Interest
Cell and Molecular Biology
Publications
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Jinadasa, T., Szabó, E.Z., Numata, M., and Orlowski, J. (2014) Activation of AMP-activated protein kinase regulates hippocampal neuronal pH by recruiting Na+/H+ exchanger NHE5 to the cell surface. J. Biol. Chem. 289(30): 20879-20897.
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Ilie, A., Weinstein, E., Boucher, A., McKinney, R.A. and Orlowski, J. (2014) Impaired posttranslational processing and trafficking of an endosomal Na+/H+ exchanger NHE6 mutant (D370WST372) associated with X-Linked intellectual disability and autism. Neurochem. Intl. 73:192-203.
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Ilie, A., Gao, A.Y.L., Reid, J., Boucher, A., McEwan, C., Barrière, H., Lukacs, G.L., McKinney, R.A., and Orlowski, J. (2016) A Christianson Syndrome-linked deletion mutation (∆287ES288) in SLC9A6 disrupts recycling endosomal function and elicits neurodegeneration and cell death. Molecular Neurodegeneration 11:63.
