Maya Saleh
Assistant Professor
Microbiology & Immunology
McGill University
Canada
Biography
McGill Life Sciences Complex, Bellini Pavillion
Research Interest
Our research interests are focused on two inter-related themes which are already considerably advanced towards identification of novel players in apoptotic cell death, and investigation of the implication of apoptosis and the “inflammasome” in inflammatory mediated immune disorders that include auto-immune disorders, inflammatory bowel disease as well as the host response to bacterial infection and sepsis. The strengths of my laboratory are based in fundamental research in apoptosis and cellular immunology, mouse models (genetic and other) of infectious diseases and inflammatory disorders and access to well-defined cohorts of patients with clinical and therapeutic subtypes of many inflammatory disorders.
Publications
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Saleh, M., Mathison, J. C., Wolinski, M. K., Bensinger, S. J., Fitzgerald, P., Ulevitch, R. J., Green, D. R. and Nicholson, D. W. (2006) "Sepsis Resistance in Caspase-12 Deficient Mice." Nature 440 : 1064-1068.
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Saleh, M. (2006) "Caspase-1 builds a new barrier to infection." Cell 126 :1028-1030.
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Nadiri, A., Wolinski, M.K., and Saleh, M. (2006) "The inflammatory caspases: Key players in the host response to pathogenic invasion and sepsis." Journal of Immunology 177 :4239-4245.
