Satya Prakash
Associate Member
Psychiatry
McGill University
Canada
Biography
Department of Biomedical Engineering
Research Interest
The primary research interests are in areas of artificial cell encapsulation, biomaterial and medical device engineering, tissue engineering, cell therapy and development of bioengineered controlled-release delivery system. The focus is to design artificial cell microcapsules that are capable of targeting specific sites and encapsulating genetically engineered cells and microorganisms, enzymes, small peptides, DNA and active drugs. Specifically, we are developing a system that integrates tissue engineering with gene and cell therapy methods with the aim to get therapeutic gene products to the targeted sites and maintain their functions for therapeutic applications by implanting live genetically engineered cells. Additionally, the research program is directed toward understanding the basic mechanisms that govern the use of microcapsules for oral delivery of therapeutic agents and developing support systems for artificial liver and kidney.
Publications
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Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine. Yoon JH, Roy Choudhury J, Park J, Prakash S, Prakash L.
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Therapeutic plasma exchange in a patient of myasthenic crisis, refractory to intravenous immunoglobulin and immunosuppressive therapy. Prakash S, Hans R, Sharma RR, Lal V, Marwaha N.
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Safety of transtympanic application of probiotics in a chinchilla animal model. Nhan C, Bezdjian A, Saha S, Prakash S, Nguyen LHP, Daniel SJ.