Timothy Kennedy
Professor
Neurology and Neurosurgery
McGill University
Canada
Biography
Dr. Timothy Kennedy’s laboratory is investigating the molecular mechanisms that direct neural development and how such mechanisms influence the organization and plasticity of the mature mammalian central nervous system. These studies aim to identify the biochemical signals that direct cells and axons to move, as well as the target-derived signals that instruct them to stop once they reach their goal and to make appropriate connections with neighboring cells.
Research Interest
cellular and molecular mechanisms that direct axon guidance, oligodendrocyte precursor migration, myelination, synapse formation and synaptic plasticity.
Publications
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Rajasekharan S, Baker KA, Horn KE, Jarjour AA, Antel JP, Kennedy TE (2009) Netrin-1 and DCC Regulate Oligodendrocyte Process Branching and Membrane Extension via Fyn and RhoA. Development, 136:415-426.
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Xu B, Goldman JS, Rymar VV, Forget C, Lo PS, Bull SJ, Vereker E, Barker PA, Trudeau LE, Sadikot AF, Kennedy TE. (2010) Critical Roles for the Netrin Receptor DCC in Dopaminergic Neuronal Precursor Migration, Axon Guidance, and Axon Arborization. Neuroscience. 169(2):932-49.
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Lai Wing Sun K, Correia JP, Kennedy TE (2011) Netrins: versatile extracellular cues with diverse functions. Development, 138(11):2153-69.
