Ursula Stochaj
Associate Professor
Department of Physiology
McGill University
Canada
Biography
our group analyzes the functional organization of the nucleus. Components of the nuclear envelope and the nuclear transport apparatus are implicated in human disease, including several types of cancer. For our studies, mammalian-cultured cells and the budding yeast Saccharomyces cerevisiae serve as model systems.
Research Interest
Cell and Molecular Biology
Publications
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Mohamed Kodiha, James G. Rassi, Claire M. Brown and Ursula Stochaj. The localization of AMP kinase is regulated by stress, cell density and signaling through the MEK→ERK1/2 pathway. Am. J. Physiol. Cell Physiol. 293: 1427 (2007)
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Xinxin Quan, Jennifer Yu, Howard Bussey and Ursula Stochaj. The localization of nuclear exporters of the importin-β family is regulated by Snf1 kinase, nutrient supply and stress. BBA Molecular Cell Research 1773: 1052 (2007)
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Mohamed Kodiha, Dan Tran, Cynthia Qian, Andreea Morogan, John Presley, Claire M. Brown and Ursula Stochaj. Oxidative stress mislocalizes and retains nuclear transport factor importin-α and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes. BBA Molecular Cell Research (2007), in press
