Youla Tsantrizos
Professor
Chemistry
McGill University
Canada
Biography
Education B.Sc. (McGill University, 1977) M.Sc. (McGill University, 1979) Ph.D. (McGill University, 1990) Postdoctoral Fellow (Brown University, 1991) Positions Held Group Leader/Distinquished Scientist (Boehringer Ingelheim, 2003-2008) Senior Research Scientist (Boehringer Ingelheim, 1998-2003) Visiting Professor (Stanford University, 1997) Assistant & Associate Professor (Concordia University, 1991-97) Professor Vanier College (1979 - 1987) Awards & Recognitions Boehringer Ingelheim Scientific Advancement Grant in Catalysis (2017) Merck, Sharpe & Dohme Grant for Translational Research (2017-2019) Boehringer Ingelheim Scientific Advancement Award in Synthesis and Medicinal Chemistry (2016) Scientific Advisory Board Member, Clearsynth (2015 – present) Past President of the Canadian Society for Chemistry (2015 – 2016) President of the Canadian Society for Chemistry (2014 – 2015) Vice President of the Canadian Society for Chemistry (2013 – 2014) Associate Editor, Frontiers in Chemical Biology (2013-present) Queen Elizabeth II Diamond Jubilee Medal 2012 Fessenden Professorships in Science Innovation, 2011 International Boehringer Ingelheim Research & Development Award, 2000 Convocation Commencement Speaker, Vanier College (1992) Dean's Honour List, McGill University 1990 Canadian Pacific Fellowship in Biotechnology, 1988-1990 Equipes et Seminnaires (Collegial) FCAR, 1986 - 1988 International Committee Member, Faculty Hiring and Promotions, Universities of Greece Committee Member, NSERC Discovery Grants Committee Member, CIHR Foundation Grants Committee Member, CIHR Prof-of-Principal Grants Committee Member, Ontario Institute for Cancer Research, Review of Investigator Award Retention and Promotion Member, NSERC CREATE Bionanomachines Member, CIHR Drug Design Training Program (DDTP)
Research Interest
Chemical Biology Synthesis/ Catalysis
Publications
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Jaeok Park, Michal Zielinski, Alexandr Magder, Youla S. Tsantrizos, Albert M. Berghuis* Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Commun. 2017, 8, 14132
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Shi-Guang Li, Zhengxu S. Han, Peter Viereck, Heewon Lee, Dmitry Kurouski, Chris H. Senanayake, Youla S. Tsantrizos Metal-Free Cycloetherification by in Situ Generated P-Stereogenic α-Diazonium Intermediates: A Convergent Synthesis of Enantiomerically Pure Dihydrobenzooxaphospholes. Org. Lett. 2017, 19, 894-897
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Jaeok Park, Chun Yuen Leung, Alexios N. Matralis, Cyrus M. Lacbay, Michail Tsakos, Guillermo Fernandez De Troconiz, Albert M. Berghuis, Youla S. Tsantrizos* Pharmacophore Mapping of Thienopyrimidine=Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. J. Med. Che. 2017 , ASAP