Jonathan D. Schertzer
Biochemistry and Biomedical Sciences
Assistant Professor Biochemistry and Biomedical Sciences HSC 4H19 McMaster University
The inability to respond to insulin is the major cause of type 2 diabetes. This insulin resistance precedes overt diabetes thereby providing therapeutic window to prevent the disease. Obesity is the main cause of insulin resistance and inflammation has emerged as a key link between obesity and insulin resistance. How does obesity cause inflammation and how does inflammation cause insulin resistance leading to diabetes? My laboratory is interested in understanding these problems in ImmunoMetabolism and how dietary and bacterial factors connect immunology and metabolism.